A new study suggests that the use of Viagra in a prolonged erection might lead to erectile dysfunction.
The findings of a small study in the British Journal of Medicine, published in this week’sJAMAshow that men taking a combination of drugs called sildenafil and tadalafil had significantly higher rates of sexual dysfunction than those taking a placebo.
The drug, known generically as sildenafil, was found in patients taking Viagra and its combination with the same components.
Researchers in the UK and France had previously shown that men who took Viagra who took the combination drug were significantly less likely to develop erectile dysfunction than those on the placebo, but that the findings were less robust.
The study also revealed that men who took the combination drug had an increase in aortic resistance to heart-to-heart surgery, which can cause heart problems in those who use the drugs.
The team also found that those on the sildenafil had a lower risk of death from cardiovascular disease than those who took the placebo, but the effect was not significant.
However, the researchers noted that there was still an association of lower overall quality of life in those taking the sildenafil with heart attack or stroke. They also noted that those taking the combination drug had a lower risk of dying from any form of cardiovascular disease compared with those on the placebo.
“The findings do not support the idea that sildenafil and tadalafil, in combination, are any better than placebo and that the combination could be associated with worse outcomes,” Dr. Emily Carter, a cardiologist and professor of medicine at the University of Pennsylvania, told.
The authors of the study noted that their findings would not be immediately reversible, but noted that they did have a small, placebo-controlled trial in the United States to see if sildenafil and tadalafil could help patients with heart disease.
Sildenafil and tadalafil are prescription drugs that are taken to treat erectile dysfunction. However, the researchers noted that the combination drug was not linked to any serious adverse effects, such as chest pain, nausea, diarrhea, or loss of appetite. The combination drug also may cause more serious side effects, including increased heart rate, angina, or a heart attack, but it should be used with caution.
Dr. Carter added that “the evidence for sildenafil and tadalafil in combination is still limited, but there is still promising evidence that these drugs can be effective in treating some patients with ED.”
The team also noted that men who used the combination drug were no more likely to have a heart attack or stroke than those who took a placebo. The drugs were not associated with any significant changes in aortic pressure. The researchers also noted that there was no difference between the two drugs in the rate of death from any form of cardiovascular disease.
“We conclude that the benefits of the combination of sildenafil and tadalafil are not likely to outweigh the potential risks,” they wrote.
The study was published in
Source: University of Pennsylvania
This article was produced by an anonymous research team at the University of Pennsylvania’s College of Medicine.This article was produced by an anonymous research team at the College of MedicineThis document has been on previouslyThis study was published in
Researchers in a new study found that sildenafil and tadalafil were “more effective in treating ED than other medications.”
The study, published in., also looked at patients with erectile dysfunction and the impact of taking the drugs together.
In particular, researchers found that sildenafil and tadalafil were significantly less effective than either drug in treating erectile dysfunction in men.
Researchers noted that the drugs were similar in their effects and that tadalafil was more effective. Sildenafil was not as effective as tadalafil and had an increased risk of death, and the combination drug also had a risk of increased heart attack.
The researchers noted that men taking sildenafil and tadalafil had an increase in the number of firings they had for erections.
Viagra has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.
Common side effects reported from Viagra use include:
More severe side effects include:
If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.
As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Viagra. Viagra can interact with bodily substances, causing potentially serious adverse reactions.
Specifically, you should inform your health care provider of any nitrate medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.
In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.
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In addition, let your doctor know if you have been diagnosed with or have had a heart attack, stroke, or heart attack during sex.
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